The Adrenal Stress Index (ASI) panel was introduced in 1989 to evaluate stress, a leading cause of morbidity and mortality. Additional tests have been added to evaluate glycemic control using multiple salivary insulin measurements, and to evaluate adrenal capacity to produce cortisol using 17-Hydroxyprogesterone.

Patient Information
Adrenal Stress Index Panel
The Diagnos-Techs™ Adrenal Stress Index (ASI) is a non-invasive way to help
evaluate the effects of stress on your body. It includes 10 tests for six different hormones and
immune markers that may be affected by chronic stress or other conditions.
The Adrenal Stress Index can:
• Help to identify possible causes of excessive fatigue
• Help your physician understand how to reduce your food cravings and build and
maintain muscle mass
• Identify underlying reasons for chronic infections such as sinusitis or other recurrent
respiratory infections
• Help your doctor to determine if a gluten-free diet may be right for you
• Identify possible reasons why you may have difficulty falling asleep or staying asleep
Four saliva samples are used to assess the following:
Cortisol Helps evaluate the stress response
Insulin Helps investigate blood sugar control
DHEA/DHEA-S Helps determine degree to which other hormones may be
affected by cortisol changes
Secretory IgA Helps evaluate the toll of stress on immunity
17-OH progesterone Helps determine underlying causes of abnormal cortisol levels
Gluten antibodies Helps identify immune response to gluten
Convenient, Simple and Thorough
• Collection is non-invasive and painless
• Samples can be conveniently
collected from your home, office
or other location
• Saliva is collected over a period of
24 hours, providing more complete
information about your body’s stress
response
• Only the free or active level of cortisol
is measured
The Adrenal Stress Index is a comprehensive
test that provides your doctor with more
information than standard serum and urine
test results.
The Adrenal Stress Index Panel
can be helpful for patients with:
• Chronic stress and stress-related
health problems
• Fatigue or lack of energy
• Muscle and joint pain or weakness
• Blood sugar dysregulation
• Osteopenia or osteoporosis
• Insomnia, sleep disturbances
or difficulty waking
• Poor memory or difficulty
retaining information
• Irritability or mood swings
• Changes in skin integrity, easy
bruising or excessive stretch marks
• Frequent or chronic infections
• Hypertension
• Increased waist-to-hip ratio or
abdominal obesity
• Anxiety or depression